Bacterial flagella and type III secretion systems
نویسندگان
چکیده
منابع مشابه
Type III secretion systems and bacterial flagella: insights into their function from structural similarities.
Type III secretion systems and bacterial flagella are broadly compared at the level of their genetic structure, morphology, regulation, and function, integrating structural information, to provide an overview of how they might function at a molecular level.
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The flagellum and the injectisome are two of the most complex and fascinating bacterial nanomachines. At their core, they share a type III secretion system (T3SS), a transmembrane export complex that forms the extracellular appendages, the flagellar filament and the injectisome needle. Recent advances, combining structural biology, cryo-electron tomography, molecular genetics, in vivo imaging, ...
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Many gram-negative plant and animal pathogenic bacteria employ a type III secretion system (T3SS) to subvert and colonize their respective host organisms. The T3SS injects effector proteins directly into the cytosol of eukaryotic cells and thus allows the manipulation of host cellular activities to the benefit of the pathogen. In plant pathogenic bacteria, T3SSs are encoded by hrp (for hypersen...
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Homologues of the protein constituents of the Klebsiella pneumoniae (Klebsiella oxytoca) type II secreton (T2S), the Pseudomonas aeruginosa type IV pilus/fimbrium biogenesis machinery (T4P) and the Methanococcus voltae flagellum biogenesis machinery (Fla) have been identified. Known constituents of these systems include (1). a major prepilin (preflagellin), (2). several minor prepilins (preflag...
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Type III secretion systems (T3SSs) are complex bacterial structures that provide gram-negative pathogens with a unique virulence mechanism enabling them to inject bacterial effector proteins directly into the host cell cytoplasm, bypassing the extracellular milieu. Although the effector proteins vary among different T3SS pathogens, common pathogenic mechanisms emerge, including interference wit...
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ژورنال
عنوان ژورنال: FEMS Microbiology Letters
سال: 2001
ISSN: 0378-1097
DOI: 10.1016/s0378-1097(01)00301-9